Darkiplier: His ego. As he says in ADWM, Dark hates being mocked. He has a sense of pride that he would do anything to protect. Even reveal a secret in order to one up you? Maybe so. Remember, Dark is self centered and jealous. Use those emotions. They very well could be the only ones Dark has.
Warfstache: His guilt. As revealed in Markiplier TV, Warfstache does have regrets. During the bubbles sketch, he is shown narrating about these very doubts and regrets. Make him think. Make him use his emotions.
Googleplier: His function. As shown in Google IRL, Googleplier will stop the task at hand to answer of fulfill a request. Eventually, this could cause him to temporarily shut down. At the very least, is buys time and really annoys him.
The Host: His reliance on powers. Because the Host can’t really “See”, the only thing allowing him to control situations is his narration. So cover his mouth. Now, he will be truly blind, unable to see whats coming and unable to do anything about it.
Doctor Iplier: His professionalism. As he states in Markiplier TV, Doctor Iplier is happy to be shown as handsome and professional. And do you know what isn’t professional? Murder. If other people are around, Dr. Iplier will hold himself back because he doesn’t want to lose his credibility.
Bim Trimmer: His pride. Bim wants the spotlight. He wants to be the center of attention and he wants to steal the show. But he wants to be appreciated. He wants to be known and famous, not ridiculed and a joke. Give him a crowd, but give him the wrong kind.
Antisepticeye: His emotion. Unlike Dark, Anti is much more… human. He gets angry. And when people are angry they become less cautious. Less attentive. If you can get Anti mad, all you need is a second person to sneak up from behind. Bam. He didn’t even see it coming.
Dr. Schneeplestein: His lack of knowledge. Dr. Schneeplestein has shown time and time again that he doesn’t really know much about biology and medical procedures. He botches operations left and right. What if he were to use his obscene techniques on himself? What if you could get him to make his mistakes but not against you?
Chase Brody: His imperfections. Chase wants to do well. He hates failing. He even shoots himself in the Bro Average video. It’s clear that failure is one of the things he fears most. Make him ashamed. Point out his flaws. It will make him upset and sad, and most of all, weak.
JackieBoy Man: His heroism. He wants to save the day. He would do anything to help. Use it against him. It’s easy to trap somebody who would wander into a black room without a weapon because he thought he heard a baby cry. Thats the kind of person JackieBoy is.
(Im sorry about how few Jack egos I did. I just don’t know them as well.)
Robbie: His Kindness. Starve him, then let him free, he is a Zombie, letting a zombie free after starving him? He will attack any living person on site ‘till he is full. When he is sane again it will destroy him knowing he killed.
